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Retatrutide 5mg
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Retatrutide 5mg
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Research record
Pending manual confirmationResearch overview
Retatrutide is a synthetic linear polypeptide comprising 39 amino acids. Its structure is based on the GIP framework and incorporates non‑natural amino acid substitutions (Aib², Aib²⁰, α‑MeLeu¹³) as well as C20 fatty acid diacid side‑chain modifications, which enhance molecular stability and serum albumin‑binding affinity. Retatrutide functions as a triple receptor agonist targeting the glucose‑dependent insulinotropic polypeptide (GIP), glucagon‑like peptide‑1 (GLP‑1), and glucagon receptors. As a single molecule, it selectively binds to and activates the GIP receptor (GIPR), GLP‑1 receptor (GLP‑1R), and glucagon receptor (GCGR) simultaneously. Through synergistic activation of these three receptors, Retatrutide enhances glucose‑dependent insulin secretion, improves glycaemic homeostasis, and promotes weight loss via multiple mechanisms, including central appetite suppression, increased energy expenditure, and enhanced lipid metabolism.
Research reference
Product FAQ
What is Retatrutide?
Retatrutide is a next‑generation peptide that activates GIP, GLP‑1, and glucagon receptors simultaneously—delivering powerful weight loss and metabolic support.
Do you sell research-grade peptides or finished pharmaceutical products?
All our peptides are research-grade with ≥99% purity. For laboratory research use only—not for human use.
What is the purity level? Do you provide a COA?
Purity is verified at ≥99% by HPLC. Each batch is accompanied by a Certificate of Analysis (COA) and mass spectrometry data.
What is the minimum order quantity? Do you accept small orders?
MOQ starts at 1 vial. Small trial orders welcome—volume discounts available.
What research areas is Retatrutide used for?
As a triple receptor agonist, Retatrutide is being studied across several key areas:
· Obesity and weight management
· Type 2 diabetes and glycemic control
· Non‑alcoholic fatty liver disease (NAFLD) / Metabolic dysfunction‑associated steatotic liver disease (MASLD)
· Cardiometabolic health
· Knee osteoarthritis (obesity‑related comorbidity)
· Obstructive sleep apnea (obesity‑related comorbidity)
Data sheet
Manual confirmation- Material Type
- Single material
- Purity Identity
- ≥99% purity
- Molecular Weight
- 4731.33 g/mol
- Pack Size
- 5mg
- Molecular Formula
- C221H342N46O68
- CAS Number
- 2381089-83-2
- Amino Acid Sequence
- YA1QGTFTSDYSIL2LDKK⁴AQA1AFIEYLLEGGPSSGAPPPS3
- PubChem CID
- 171390338
- Storage conditions overview
- Storage typeLong-termTemperature-80℃Duration2-3 yearsNotesSealed, dark, minimal openingStorage typeStandardTemperature-20℃Duration1-2 yearsNotesSealed, dark, moisture-proofStorage typeShort-termTemperature4℃Duration1-2 weeksNotesTemporary storage, use promptlyStorage typeWorking SolutionTemperature4℃Duration1-7 daysNotesReconstituted, short-term, avoid freeze-thaw
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