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Tesamorelin 5mg

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Products/Tesamorelin 5mg

Tesamorelin 5mg

Tesamorelin 5mg

Important NoticeThis product is for use only in vitro research. It is strictly prohibited for human injection, clinical treatment, food addition or any animal experiments. Please read our terms and conditions carefully before placing an order.
Purity / identity≥99% purity
Molecular weight5135.78 g/mol
Pack size5mg

Volume pricing

Configured totals update at each quantity threshold.

Configured total$34.88
Open COA / MSDS
SKU: ps-tesamorelin-5mg

Research record

Pending manual confirmation

Research overview

Tesamorelin is a synthetic 44‑amino‑acid peptide analogue and a stabilized, modified version of human growth hormone‑releasing hormone (GHRH). Its N‑terminus is modified (conjugated with a 3‑hexenyl group) to enhance molecular stability and pharmacokinetic properties. Tesamorelin activates GHRH receptors in the pituitary gland, stimulating the synthesis and pulsatile release of endogenous growth hormone (GH), which in turn acts on peripheral targets such as the liver to promote insulin‑like growth factor‑1 (IGF‑1) production. In addition, research has shown that it reduces hepatic fat content and slows fibrosis progression in non‑alcoholic fatty liver disease (NAFLD). Tesamorelin is currently the only drug approved in the United States for the reduction of abdominal fat in patients with HIV‑associated lipodystrophy.

Research reference

Product FAQ

What is Tesamorelin?

Tesamorelin is a synthetic 44-amino acid peptide analogue of endogenous growth hormone-releasing hormone (GHRH). It works by binding to and activating GHRH receptors in the anterior pituitary, stimulating the pulsatile release of growth hormone (GH), which in turn regulates fat metabolism and body composition. It was approved by the FDA in 2010 under the brand name Egrifta®.

What is the mechanism of action of Tesamorelin?

As a GHRH analogue, tesamorelin binds to GHRH receptors in the pituitary, stimulating the synthesis and pulsatile release of GH. Elevated GH levels promote the production of IGF-1 in the liver and peripheral tissues, exerting dual effects of lipolysis (breaking down visceral fat) and anabolism (increasing lean body mass). Compared to direct GH injection, this pulsatile release pattern more closely mimics the physiological state and offers a better safety profile.

Does Tesamorelin have research value for NAFLD?

Yes. Given its significant reduction in hepatic fat percentage, Tesamorelin is being actively investigated in NAFLD. A clinical trial in obese NAFLD patients is evaluating whether tesamorelin can reduce liver fat and improve inflammation and fibrosis. Early evidence suggests beneficial effects on liver fat with no observed hepatotoxicity.

What are the main research areas for Tesamorelin?

· HIV‑associated lipodystrophy (visceral fat accumulation) — FDA‑approved indication

· Non‑alcoholic fatty liver disease (NAFLD) / MASLD

· Obesity and abdominal fat accumulation

· Hip fracture recovery

· Sleep disorders

· Mild cognitive impairment

Data sheet

Manual confirmation
Material Type
Single material
Purity Identity
≥99% purity
Molecular Weight
5135.78 g/mol
Pack Size
5mg
Molecular Formula
C221H366N72O67S
CAS Number
218949-48-5
Amino Acid Sequence
YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL
PubChem CID
16137828
Storage conditions overview
Storage typeLong-termTemperature-80°CDuration2-3 yearsNotesSealed, dark, minimal opening
Storage typeStandardTemperature-20°CDuration1-2 yearsNotesSealed, dark, moisture-proof
Storage typeShort-termTemperature4°CDuration1-2 weeksNotesTemporary storage, use promptly
Storage typeWorking SolutionTemperature4°CDuration1-7 daysNotesReconstituted, short-term, avoid freeze-thaw

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