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GHK-Cu: Copper-Complex Source Methods and Documentation Review

A research-use-only review of a defined GHK copper-complex study, its analytical methods, and separate material documentation.

Published Updated Published byPeptides Bio

Research or raw-material evaluation only. Not for human or veterinary use.

Related research material

GHK-Cu 50 mg

This page brings the GHK-Cu product profile, analytical quality record and published copper-complex research into one practical overview.

GHK-Cu 50 mg gives researchers a clearly identified copper-complex material with a strong analytical profile and published chemistry and wound-model research. The product record and COA for lot GK50-01-905-g387, analysed 20 November 2025, report 99.88% HPLC area purity, 52.27 mg net peptide quantity, conforming retention time, blue-to-off-blue lyophilized powder and endotoxin conforming to ≤0.5 EU/mg.

GHK-Cu article diagram showing how published complex-study evidence and the product material record add context together
How the GHK-Cu study evidence and product material record support a clearer research discussion.

GHK-Cu 50 mg product summary

Field Specification / result Project value
Material label GHK-Cu / Gly-His-Lys-Cu Clear chemical naming for product and literature searches.
Pack size 50 mg Useful quantity planning for research workflows.
Formula / molecular weight C14H22CuN6O4 / 401.91 g/mol Core identifiers for documentation and method planning.
HPLC purity 99.88% area A strong analytical quality reference reported by the COA.
Net peptide quantity 52.27 mg Supports concentration and quantity planning.
Appearance / endotoxin Blue-to-off-blue lyophilized powder; endotoxin conforms Quality-control details available in the product record.

What the experiments found

Conato et al. examined GHK and two synthetic analogues with potentiometry, solution calorimetry, UV–VIS spectrophotometry, circular dichroism and electron-paramagnetic-resonance spectroscopy. The ligands formed complexes with different stoichiometries and stabilities, with evidence for binuclear species. These findings help researchers understand copper-complex behaviour under defined analytical conditions. See the PubMed record.

In a separate rat wound-chamber experiment, GHK-Cu was associated with concentration-dependent increases in dry weight, DNA, total protein, collagen and glycosaminoglycan content; collagen synthesis was reported as twice that of non-collagen proteins. The study adds a concrete in-vivo research reference to the chemistry profile. See the rat study.

Why this evidence is useful together

  1. Product record: gives the material name, formula, pack size and analytical profile.
  2. Chemistry study: adds coordination, stoichiometry and stability context.
  3. Wound-model study: adds a defined in-vivo research reference.

Planning a GHK-Cu research project

  • Define the target model and analytical endpoint before selecting the material format.
  • Use the formula, molecular weight and pack size to prepare a clear project brief.
  • Link the product profile to the chemistry and wound-model literature when discussing the project.
  • Contact the team for pricing, availability and a documentation package.

Next step

Start from the GHK-Cu 50 mg product page, then use the contact page for pricing, availability and a project documentation package. The COA, MSDS and batch-record review is available for teams that want a deeper documentation workflow.

Sources

Need a quote, availability check or documentation package? Contact our team with the material name, pack size and project requirements.

References

  1. Conato et al., copper complexes of GHK and synthetic analogues, PMID 11325542

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