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GHK-Cu 50mg

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RESEARCH USE ONLYRUO

GHK-Cu 50mg

Purity / identity≥99% purity
Molecular weight401.91 g/mol
Pack size50mg

Volume pricing

Configured totals update at each quantity threshold.

Configured total$16.65
Open COA / MSDS
SKU: ps-ghk-cu-50mg

Research record

Pending manual confirmation

Research overview

GHK‑Cu (copper peptide, also known as blue copper peptide) is a naturally occurring small‑molecule complex formed by the association of the tripeptide glycine‑histidine‑lysine with copper ions (Cu²⁺). This peptide exhibits remarkable copper‑binding and transport properties. The core mechanism of GHK‑Cu lies in its profound modulation of gene expression—it can influence the activity of thousands of human genes, upregulating those involved in antioxidant defense and tissue repair while downregulating genes associated with inflammation and tissue damage. More specifically, GHK‑Cu stimulates collagen, elastin, and glycosaminoglycan synthesis in fibroblasts, promotes angiogenesis, and suppresses inflammatory responses via downregulation of the JAK1 pathway and reduction of reactive oxygen species (ROS) production. In recent years, it has also shown potential in research on aging‑related cognitive function.

Research reference

Product FAQ

What is GHK‑Cu?

GHK‑Cu (copper peptide) is a naturally occurring tripeptide composed of glycine‑histidine‑lysine (GHK) complexed with a copper ion (Cu²⁺). It is naturally found in human plasma, saliva, and urine, but its concentration decreases significantly with age. GHK‑Cu has been extensively studied for its wound healing, tissue repair, and skin regeneration properties.

What is the mechanism of action of GHK‑Cu?

GHK‑Cu works through multiple mechanisms:

· Copper ion delivery: Delivers copper ions to cells, where copper serves as a cofactor for various enzymes (e.g., superoxide dismutase, lysyl oxidase)

· Gene expression modulation: GHK‑Cu has been shown to modulate the expression of over 4,000 human genes

· Anti‑inflammatory effects: Suppresses the production of pro‑inflammatory factors (TNF‑α, IL‑1β, IL‑6)

· Promoting cell migration and proliferation: Enhances fibroblast and keratinocyte migration and proliferation, accelerating wound closure

· Antioxidant effects: Reduces ROS production and protects cells from oxidative stress

Is GHK‑Cu a banned substance?

GHK‑Cu is not currently listed on the WADA Prohibited List. It has a distinct mechanism of action and is not considered a growth hormone releaser or performance enhancer

Does GHK‑Cu have research value for hair growth?

Yes. Studies show that GHK‑Cu promotes hair follicle stem cell proliferation, increases follicle diameter and the anagen/telogen ratio in vitro. Topical application of GHK‑Cu has demonstrated hair regeneration and increased follicle counts in animal models, making it potentially valuable in androgenetic alopecia research.

What are the main research areas for GHK‑Cu?

· Skin wound healing and scar repair

· Anti‑aging and skin regeneration

· Hair growth and follicle repair

· Anti‑inflammation and antioxidant effects

· Nervous system protection

· Cancer research

· Tissue angiogenesis (blood vessel formation)

Data sheet

Manual confirmation
Material Type
Single material
Purity Identity
≥99% purity
Molecular Weight
401.91 g/mol
Pack Size
50mg
Molecular Formula
C14H22CUN6O4
CAS Number
89030-95-5
Amino Acid Sequence
Gly-His-Lys-Cu
PubChem CID
71587328
Storage conditions overview
Storage typeLong-termTemperature-80°CDuration2-3 yearsNotesSealed, dark, minimal opening
Storage typeStandardTemperature-20°CDuration1-2 yearsNotesSealed, dark, moisture-proof
Storage typeShort-termTemperature4°CDuration1-2 weeksNotesTemporary storage, use promptly
Storage typeWorking SolutionTemperature4°CDuration1-7 daysNotesReconstituted, short-term, avoid freeze-thaw